Ephraim Wildes was born in Topsfield, Massachusetts, in February 1665, the son of John and his second wife Sarah (Averill) Wildes. He served as town treasurer and constable in Topsfield, and later as selectman, juror, and grand juror. He married Mary Howlett in 1689; their surviving children included John, Mary, Ephraim, Jonathan, Susannah, Sarah, Dorothy, Jacob, Priscilla, Samuel, Hannah, Amos, Nathan, and Elijah. Ephraim Wildes died on April 2, 1725, in Topsfield.

John Wildes was born on June 25, 1690, in Topsfield, the son of Ephraim and Mary Wildes. He was a house wright in Topsfield and was active in town affairs, acting as moderator of town meetings twenty-two times and elected selectman in thirteen years. He married Phebe Perkins in about 1714; their surviving children included John, Katherine, Zebulon, Elisha, Sarah, and Amos. John Wildes died on September 27, 1750, in Topsfield.

Elisha Wildes was born on September 23, 1720, in Topsfield, the son of John and Phebe Wildes. He served as constable and selectman in Topsfield. He married Mary Bradstreet in 1754, and their children included Sylvanus, Mehitable, and Sarah. Elisha Wildes died on June 26, 1787, in Topsfield.