The 2nd Regiment Massachusetts Volunteer Heavy Artillery was organized at Readville, Massachusetts and officially mustered into service from July 1863 until December 1863.The regiment was assigned to garrison duties in Virginia and North Carolina. Company M was commanded by Captain Jere A. Greely of Salisbury and mustered into service on December 24, 1863. The company was assigned to duties in Norfolk and Portsmouth, Virginia followed by duties at New Berne, North Carolina. The regiment was officially mustered out of service on September 23, 1865.

This series includes correspondence, orders, invoices, muster rolls, clothing receipt rolls, and monthly and quarterly returns of clothing, camp, and garrison equipage, related to the 2nd Regiment Massachusetts Volunteer Heavy Artillery. Correspondence is addressed to Jere A. Greely, captain of Company M.